Benzaldehyde → 1-Benzyl-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)piperidine
Reaction equation
[C:41]([O:42][BH-:43]([O:44][C:45](=[O:46])[CH3:47])[O:48][C:49](=[O:50])[CH3:51])(=[O:52])[CH3:53].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:57][OH:58].[CH3:59][CH2:60][O:61][CH2:62][CH3:63].[CH:33](=[O:34])[c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[Cl:2][c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[C:12]2([c:18]3[c:19]([F:25])[cH:20][cH:21][c:22]([F:24])[cH:23]3)[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:7][cH:8]1.[Cl:64][CH2:65][Cl:66].[ClH:1].[Na+:54].[Na+:56].[OH-:55]>>[Cl:2][c:3]1[cH:4][cH:5][c:6]([S:9](=[O:10])(=[O:11])[C:12]2([c:18]3[c:19]([F:25])[cH:20][cH:21][c:22]([F:24])[cH:23]3)[CH2:13][CH2:14][N:15]([CH2:33][c:35]3[cH:36][cH:37][cH:38][cH:39][cH:40]3)[CH2:16][CH2:17]2)[cH:7][cH:8]1Participants
11
Reactant 10
Product 1
Sources & evidence
- ORD record
- ord-d0c06548ac524f38a0cf4aa9951cc3ba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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