Tetrahydrofuran → 2-(6-Fluoropyridin-3-yl)-2-methylpropan-1-ol
Reaction equation
[Al+3:2].[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:24][CH2:25][O:26][C:27]([CH3:28])=[O:29].[F:7][c:8]1[cH:9][cH:10][c:11]([C:14]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])([CH3:22])[CH3:23])[cH:12][n:13]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[F:7][c:8]1[cH:9][cH:10][c:11]([C:14]([CH2:15][OH:16])([CH3:22])[CH3:23])[cH:12][n:13]1Participants
7
Sources & evidence
- ORD record
- ord-7f0036e260dc4f16820fae3191b41fa6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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