Potassium Cation → 5-(1H-pyrazol-1-yl)pyrimidin-2-amine

HRID 682728Notes

Reaction equation

HRID 682728 reaction equation
[Br:6][c:7]1[cH:8][n:9][c:10]([NH2:13])[n:11][cH:12]1.[C:24](=[O:25])([O-:26])[O-:27].[CH3:14][NH:15][CH:16]1[CH2:17][CH2:18][CH2:19][CH2:20][CH:21]1[NH:22][CH3:23].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cu:35][I:36].[K+:28].[K+:29].[nH:1]1[n:2][cH:3][cH:4][cH:5]1>>[n:1]1(-[c:7]2[cH:8][n:9][c:10]([NH2:13])[n:11][cH:12]2)[n:2][cH:3][cH:4][cH:5]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 1048PyrazoleHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 2313102-Amino-5-bromopyrimidineHCID 5510741-N,2-N-dimethylcyclohexane-1,2-diamine

Product 1

HCID 672249655-(1H-pyrazol-1-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-b37060a98ebf4d679ff567b36125e29d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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