Hydrochloric Acid → {5-[N-(cyclopentylmethyl)-N-ethylamino]-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl}methanol

HRID 683748Notes

Reaction equation

HRID 683748 reaction equation
[BH4-:38].[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:40][O:41][CH:42]([OH:43])[CH3:44].[CH3:50][CH2:51][OH:52].[CH:1]1([CH2:6][N:7]([CH2:8][CH3:9])[c:10]2[c:11]([C:20]#[N:21])[cH:12][c:13]3[c:14]([n:15]2)[cH:16][cH:17][n:18]3[CH3:19])[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:32][C:33](=[O:34])[O:35][CH2:36][CH3:37].[ClH:24].[Na+:23].[Na+:39].[OH-:22]>>[CH:1]1([CH2:6][N:7]([CH2:8][CH3:9])[c:10]2[c:11]([CH2:20][OH:34])[cH:12][c:13]3[c:14]([n:15]2)[cH:16][cH:17][n:18]3[CH3:19])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

11

Reactant 10

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ion2×HCID 961HydroxideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 28123BorohydrideHCID 30156371-MethoxyethanolHCID 578612815-[N-(cyclopentylmethyl)-N-ethylamino]-methyl-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile

Product 1

HCID 57861257{5-[N-(cyclopentylmethyl)-N-ethylamino]-1-methyl-1H-pyrrolo[3,2-b]pyridin-6-yl}methanol

Sources & evidence

ORD record
ord-398433c284a148baa06968a96253b1f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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