Tetrahydrofuran → HCID 74928714, compound

HRID 683859Notes

Reaction equation

HRID 683859 reaction equation
[CH2:67]1[O:68][CH2:69][CH2:70][CH2:71]1.[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:31]2[c:32]([CH3:38])[cH:33][cH:34][c:35]([F:37])[cH:36]2)[NH:13][C:14](=[O:30])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][C:25]([CH2:26][OH:27])([CH3:28])[CH3:29])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1.[N:58]1([CH2:64][CH2:65][NH2:66])[CH2:59][CH2:60][CH2:61][CH2:62][CH2:63]1.[OH:39][n:40]1[c:41]2[c:42]([cH:43][cH:44][cH:45][cH:46]2)[n:47][n:48]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[C:6]21[CH:12]([c:31]2[c:32]([CH3:38])[cH:33][cH:34][c:35]([F:37])[cH:36]2)[NH:13][C:14](=[O:30])[CH2:15][CH:16]1[c:17]1[c:18]([O:24][C:25]([C:26](=[O:27])[NH:66][CH2:65][CH2:64][N:58]2[CH2:59][CH2:60][CH2:61][CH2:62][CH2:63]2)([CH3:28])[CH3:29])[cH:19][cH:20][c:21]([Cl:23])[cH:22]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 33944N-(2-Aminoethyl)piperidineHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 765678856-chloro-4'-[5-chloro-2-(2-hydroxy-1,1-dimethyl-ethoxy)phenyl]-2'-[5-fluoro-2-methylphenyl]spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

Product 1

HCID 74928714HCID 74928714, compound

Sources & evidence

ORD record
ord-ed7322e1c085477caeb8676d1b04ea0a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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