Tetrahydrofuran → 1-(4-Ethoxy-phenyl)-1-(2-fluoro-3-(3-phenoxyphenyl)prop-1-enyl)cyclopropane

HRID 684208Notes

Reaction equation

HRID 684208 reaction equation
[C:16]([O:17][CH2:20][C:21](=[CH:22][C:23]1([c:26]2[cH:27][cH:28][c:29]([O:32][CH2:33][CH3:34])[cH:30][cH:31]2)[CH2:24][CH2:25]1)[F:35])(=[O:18])[CH3:19].[Mg:15].[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][c:10]([Br:14])[cH:11][cH:12][cH:13]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[O:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][c:10]([CH2:20][C:21](=[CH:22][C:23]2([c:26]3[cH:27][cH:28][c:29]([O:32][CH2:33][CH3:34])[cH:30][cH:31]3)[CH2:24][CH2:25]2)[F:35])[cH:11][cH:12][cH:13]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 961653-Bromodiphenyl etherHCID 5462224MagnesiumHCID 543885951-(3-Acetoxy-2-fluoroprop-1-enyl)-1-(4-ethoxyphenyl)cyclopropane

Product 1

HCID 543416001-(4-Ethoxy-phenyl)-1-(2-fluoro-3-(3-phenoxyphenyl)prop-1-enyl)cyclopropane

Sources & evidence

ORD record
ord-06c1d9c0e665449daaaa95d06799231e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…