Dimethylformamide → N-[1-[8-acetyl-3-(4-ethoxyphenyl)-4-oxo-6,7-dihydro-5H-pyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-[(2,5-dimethylpyrazol-3-yl)methyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]acetamide
Reaction equation
[C:27]([CH3:28])(=[O:29])[N:30]1[CH2:31][CH2:32][CH2:33][c:34]2[c:35]1[n:36][c:37]([CH:50]([CH3:51])[NH:52][CH2:53][c:54]1[n:55]([CH3:60])[n:56][c:57]([CH3:59])[cH:58]1)[n:38](-[c:41]1[cH:42][cH:43][c:44]([O:47][CH2:48][CH3:49])[cH:45][cH:46]1)[c:39]2=[O:40].[CH3:22][N:23]([CH3:24])[CH:25]=[O:26].[CH3:61][CH2:62][N:63]([CH2:64][CH3:65])[CH2:66][CH3:67].[Cl:16][C:17]([C:18]([Cl:19])=[O:20])=[O:21].[Cl:68][CH2:69][Cl:70].[F:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([CH2:8][C:9](=[O:10])[OH:11])[cH:6][cH:7]1>>[F:1][c:2]1[c:3]([C:12]([F:13])([F:14])[F:15])[cH:4][c:5]([CH2:8][C:9](=[O:11])[N:52]([CH:50]([c:37]2[n:36][c:35]3[c:34]([c:39](=[O:40])[n:38]2-[c:41]2[cH:42][cH:43][c:44]([O:47][CH2:48][CH3:49])[cH:45][cH:46]2)[CH2:33][CH2:32][CH2:31][N:30]3[C:27]([CH3:28])=[O:29])[CH3:51])[CH2:53][c:54]2[n:55]([CH3:60])[n:56][c:57]([CH3:59])[cH:58]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b36ed4e79f4041faac8d5b1e7035fa26
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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