Tetrahydrofuran → 2-Hydroxy-3-bromo-4-chloro-5-(1,1-dimethylethyl)benzonitrile
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[F:17][C:18]([F:19])([F:20])[C:21]([O:22][C:23](=[O:24])[C:25]([F:26])([F:27])[F:28])=[O:29].[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1.[OH:1][c:2]1[c:3]([CH:4]=[N:5][OH:6])[cH:7][c:8]([C:13]([CH3:14])([CH3:15])[CH3:16])[c:9]([Cl:12])[c:10]1[Br:11]>>[OH:1][c:2]1[c:3]([C:4]#[N:5])[cH:7][c:8]([C:13]([CH3:14])([CH3:15])[CH3:16])[c:9]([Cl:12])[c:10]1[Br:11]Participants
5
Sources & evidence
- ORD record
- ord-d2a9b7a63be74820b0ab3b17ca1698b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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