Chloride → 2-(5-(1,3-Dioxan-2-yl)pyridin-2-yl)-7-chlorothieno[3,2-b]pyridine
Reaction equation
[Br:16][c:17]1[n:18][cH:19][c:20]([CH:23]2[O:24][CH2:25][CH2:26][CH2:27][O:28]2)[cH:21][cH:22]1.[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:11][CH2:12][CH2:13][CH2:14][Li:15].[Cl-:34].[Cl-:36].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][cH:9][s:10]2.[Zn+2:35].[cH:37]1[cH:38][cH:39][c:40]([P:41]([Pd:42]([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[P:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[cH:112][cH:113]1>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:17]1[n:18][cH:19][c:20]([CH:23]3[O:24][CH2:25][CH2:26][CH2:27][O:28]3)[cH:21][cH:22]1)[s:10]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9830d4901b054082a81d446bb6deeb61
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…