Tetrahydrofuran → 2-(cyclopropylmethoxy)-1H-isoindole-1,3(2H)-dione

HRID 689990Notes

Reaction equation

HRID 689990 reaction equation
[CH:13]1([CH2:16][OH:17])[CH2:14][CH2:15]1.[O:37]=[C:38]([O:39][CH2:40][CH3:41])[N:42]=[N:43][C:44]([O:45][CH2:46][CH3:47])=[O:48].[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1.[OH:1][N:2]1[C:3](=[O:12])[c:4]2[c:5]([cH:8][cH:9][cH:10][cH:11]2)[C:6]1=[O:7].[c:18]1([P:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:32][cH:33][cH:34][cH:35][cH:36]1>>[O:1]([N:2]1[C:3](=[O:12])[c:4]2[c:5]([cH:8][cH:9][cH:10][cH:11]2)[C:6]1=[O:7])[CH2:16][CH:13]1[CH2:14][CH2:15]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 10665N-HydroxyphthalimideHCID 11776TriphenylphosphineHCID 75644CyclopropanemethanolHCID 220568ethyl N-ethoxycarbonyliminocarbamate

Product 1

HCID 14843102-(cyclopropylmethoxy)-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-1faefa700fb34c5a9c6fff020e238281
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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