4-Methylmorpholine → [2-({1-[3,4-Difluoro-2-(2-fluoro-4-iodo-phenylamino)-phenyl]-methanoyl}-aminooxy)-ethyl]-methyl-carbamic acid tert-butyl ester
Reaction equation
[C:43]([CH3:44])([CH3:45])([CH3:46])[O:47][C:48]([N:49]([CH3:50])[CH2:51][CH2:52][O:53][NH2:54])=[O:55].[CH3:21][N:22]1[CH2:23][CH2:24][O:25][CH2:26][CH2:27]1.[CH3:61][CH2:62][O:63][C:64](=[O:65])[CH3:66].[F:1][c:2]1[c:3]([NH:12][c:13]2[c:14]([F:20])[cH:15][c:16]([I:19])[cH:17][cH:18]2)[c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][c:10]1[F:11].[O:56]1[CH2:57][CH2:58][CH2:59][CH2:60]1.[c:28]1([P:29]([Cl:30])([c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)=[O:37])[cH:38][cH:39][cH:40][cH:41][cH:42]1>>[F:1][c:2]1[c:3]([NH:12][c:13]2[c:14]([F:20])[cH:15][c:16]([I:19])[cH:17][cH:18]2)[c:4]([C:5](=[O:7])[NH:54][O:53][CH2:52][CH2:51][N:49]([C:48]([O:47][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:55])[CH3:50])[cH:8][cH:9][c:10]1[F:11]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5c20d374c74c4146bab05af8af7b3c86
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…