Ammonium → 1-Benzyl-3-(5-chloro-2-fluorobenzyl)pyrrolidin-3-ol
Reaction equation
[Br:3][CH2:4][c:5]1[c:6]([F:12])[cH:7][cH:8][c:9]([Cl:11])[cH:10]1.[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[N:20]1[CH2:21][C:22](=[O:25])[CH2:23][CH2:24]1.[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[Cl-:26].[I:2].[Mg:1].[NH4+:27]>>[CH2:4]([c:5]1[c:6]([F:12])[cH:7][cH:8][c:9]([Cl:11])[cH:10]1)[C:22]1([OH:25])[CH2:21][N:20]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:24][CH2:23]1Participants
8
Sources & evidence
- ORD record
- ord-3c6a7bc44895427383cbbd05ec6dc2e1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…