Hydrochloric Acid → 2-(4-chloro-phenyl)-N-[3-(2,6-dioxo-piperidin-3-yl)-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl]-acetamide

HRID 697401Notes

Reaction equation

HRID 697401 reaction equation
[C:12]([n:13]1[cH:14][cH:15][n:16][cH:17]1)([n:18]1[cH:19][cH:20][n:21][cH:22]1)=[O:23].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][C:9](=[O:10])[OH:11])[cH:6][cH:7]1.[ClH:24].[NH2:25][CH2:26][c:27]1[cH:28][c:29]2[c:30](=[O:46])[n:31]([CH:38]3[C:39](=[O:45])[NH:40][C:41](=[O:44])[CH2:42][CH2:43]3)[c:32]([CH3:37])[n:33][c:34]2[cH:35][cH:36]1.[O:47]=[CH:48][N:49]([CH3:50])[CH3:51]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][C:9](=[O:11])[NH:25][CH2:26][c:27]2[cH:28][c:29]3[c:30](=[O:46])[n:31]([CH:38]4[C:39](=[O:45])[NH:40][C:41](=[O:44])[CH2:42][CH2:43]4)[c:32]([CH3:37])[n:33][c:34]3[cH:35][cH:36]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 15880(4-Chlorophenyl)acetic acidHCID 682631,1'-CarbonyldiimidazoleHCID 252357323-[6-(Aminomethyl)-2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl]piperidine-2,6-dione

Product 1

HCID 252358662-(4-chloro-phenyl)-N-[3-(2,6-dioxo-piperidin-3-yl)-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl]-acetamide

Sources & evidence

ORD record
ord-1def4f53e3ca47868987b189a3c56c4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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