Chloroform → 1-[3-Hydroxy-4-(tritylamino)pyrrolidin-1-yl]-2-[4-(trifluoromethoxy)phenyl]ethanone
Reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH:49]([Cl:50])([Cl:51])[Cl:52].[NH2:1][CH:2]1[CH2:3][N:4]([C:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:16][C:17]([F:18])([F:19])[F:20])[cH:14][cH:15]2)=[O:21])[CH2:5][CH:6]1[OH:7].[c:29]1([C:35]([c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)[Cl:48])[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[NH:1]([CH:2]1[CH2:3][N:4]([C:8]([CH2:9][c:10]2[cH:11][cH:12][c:13]([O:16][C:17]([F:18])([F:19])[F:20])[cH:14][cH:15]2)=[O:21])[CH2:5][CH:6]1[OH:7])[C:35]([c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)([c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)[c:42]1[cH:43][cH:44][cH:45][cH:46][cH:47]1Participants
6
Sources & evidence
- ORD record
- ord-d51251e59e914208964a69569904c131
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…