Tetrahydrofuran → 4-(4-Morpholinylmethyl)-2-thiazolemethanol

HRID 698132Notes

Reaction equation

HRID 698132 reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:18][CH:19]([CH2:20][AlH:21][CH2:22][CH:23]([CH3:24])[CH3:25])[CH3:26].[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][c:8]2[n:9][c:10]([C:13](=[O:14])[O:15][CH2:16][CH3:17])[s:11][cH:12]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][c:8]2[n:9][c:10]([CH2:13][OH:14])[s:11][cH:12]2)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 14487Diisobutylaluminum hydrideHCID 67334313Ethyl 4-(morpholin-4-ylmethyl)-1,3-thiazole-2-carboxylate

Product 1

HCID 673343194-(4-Morpholinylmethyl)-2-thiazolemethanol

Sources & evidence

ORD record
ord-ea5b5636258845cc901235ae2073aae5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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