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HRID69948

反应详情

EQUATION

反应方程式

HRID 69948 的结构方程式

REACTANTS

反应物

2
结构：CSc1nc(N)cc(Cl)n1
HCID70496

4-Amino-6-chloro-2-methylthiopyrimidine

C5H6ClN3S

结构：CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
HCID90495

Di-tert-butyl dicarbonate

C10H18O5

PRODUCTS

生成物

1
结构：CSc1nc(Cl)cc(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)n1
HCID86669199

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)c1ccncc1
催化剂HCID14284

N,N-Dimethylpyridin-4-amine

C7H10N2

PROCEDURE

实验过程

Method 24 was followed using 6-chloro-2-(methylthio)pyrimidin-4-amine (1.0 equiv.), BOC2O (2.0 equiv.), and DMAP (cat.) to afford 6-chloro-N,N-di-BOC-2-(methylthio)pyrimidin-4-amine in >95%. LCMS (m/z): 376.1 (MH+); LC Rt=4.9 min.