Benzyl Chloride → HCID 67119738, compound

HRID 70007Notes

Reaction equation

HRID 70007 reaction equation
C([O-])([O-])=O.[K+].[K+].[OH:7][C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([OH:18])[CH:16]=2)[CH:11]=[CH:10][C:9]=1[C:19]([OH:21])=[O:20].[CH2:22](Cl)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>CN(C=O)C>[CH2:22]([O:20][C:19]([C:9]1[CH:10]=[CH:11][C:12]2[C:17](=[CH:16][C:15]([O:18][CH2:22][C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:14][CH:13]=2)[C:8]=1[O:7][CH2:19][C:9]1[CH:10]=[CH:11][CH:12]=[CH:17][CH:8]=1)=[O:21])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 198229011,7-Dihydroxynaphthalene-2-carboxylic acid

Product 1

HCID 67119738HCID 67119738, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

K2CO3 (2.88 g, 20.0 mmol), dry DMF (6.4 mL), 1,7-Dihydroxy-naphthalene-2-carboxylic acid (0.635 g, 3.11 mmol), and benzyl chloride (1.72 mL). Yield: 0.805 g of golden brown viscous product (55%, 2 steps).

Sources & evidence

ORD record
ord-04b760b2af634a32aba02e9cbaca6552
Source dataset
uspto-grants-2014_09
Patent number
US08822515B2

Reaction notes

Loading…