1,2-Dichloroethane → 6-chloro-4-(5-(4-hydroxy-4-methylpiperidine-1-carbonyl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-one

HRID 702003Notes

Reaction equation

HRID 702003 reaction equation
[CH2:47]([Cl:48])[CH2:49][Cl:50].[CH3:20][C:21]1([OH:27])[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46].[Cl:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([C:15](=[O:16])[OH:17])[cH:18][cH:19]2)[c:5](=[O:9])[n:6]([CH3:8])[n:7]1.[O:51]=[CH:52][N:53]([CH3:54])[CH3:55].[OH:28][n:29]1[c:30]2[c:31]([cH:32][cH:33][cH:34][cH:35]2)[n:36][n:37]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([C:15](=[O:17])[N:24]3[CH2:23][CH2:22][C:21]([CH3:20])([OH:27])[CH2:26][CH2:25]3)[cH:18][cH:19]2)[c:5](=[O:9])[n:6]([CH3:8])[n:7]1

Participants

7

Reactant 6

HCID 111,2-DichloroethaneHCID 6228DimethylformamideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 156491744-Methylpiperidin-4-olHCID 667425116-(6-Chloro-2-methyl-3-oxo-2,3-dihydropyridazin-4-ylamino)nicotinic acid

Product 1

HCID 667423526-chloro-4-(5-(4-hydroxy-4-methylpiperidine-1-carbonyl)pyridin-2-ylamino)-2-methylpyridazin-3(2H)-one

Sources & evidence

ORD record
ord-f62a52460fcb48e5a82c46b569bf4b27
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…