Tetrahydrofuran → 2-butyl-9,9-dimethyl-6,7,8,9-tetrahydro-5H-benzo-cycloheptene

HRID 702029Notes

Reaction equation

[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([CH3:12])([CH3:13])[CH2:8][CH2:9][CH2:10][CH2:11]2.[Cu:20][I:21].[I:15][CH2:16][CH2:17][CH2:18][CH3:19].[O:22]1[CH2:23][CH2:24][CH2:25][CH2:26]1>>[c:2]1([CH2:16][CH2:17][CH2:18][CH3:19])[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[C:7]([CH3:12])([CH3:13])[CH2:8][CH2:9][CH2:10][CH2:11]2

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 10962Butyl iodide

HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)

HCID 230025142-bromo-6,7,8,9-tetrahydro-9,9-dimethyl-5H-benzocycloheptene

Product 1

HCID 230025072-butyl-9,9-dimethyl-6,7,8,9-tetrahydro-5H-benzo-cycloheptene

Sources & evidence

ORD record: ord-2577531d384043d48b3edfd85394fa56
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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