Water → Tert-butyl (5-((trimethylsilyl)ethynyl)thiazol-2-yl)carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([Br:13])[cH:11][n:12]1)=[O:14].[CH3:15][Si:16]([CH3:17])([CH3:18])[C:19]#[CH:20].[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[Cu:29][I:30].[OH2:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[s:9][c:10]([C:20]#[C:19][Si:16]([CH3:15])([CH3:17])[CH3:18])[cH:11][n:12]1)=[O:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f00ffefdf3a34433997f933de057b6de
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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