反应详情

Working as described in Example 3 but replacing 2-(2-chloroethyl)-6,7-dimethoxy-1(2H)-phthalazinone with an equivalent amount of 2-(3-chloropropyl)-6,7-dimethoxy-1(2H)-phthalazinone obtained as described in Example 13, and replacing N-phenylpiperazine with an equivalent amount of 4-(4-fluorobenzoyl)-piperazine, 2-{3-[4-(4-fluorobenzoyl)-piperidin-1-yl]-propyl}-6,7-dimethoxy-1(2H)-phthalazinone hydrochloride is obtained (m.p. 250°-252° C., from ethyl acetate).

1. customobtained