反应详情

1.0 M LiOH (0.266 mL, 0.266 mmol) was added to a solution of 2D (225 mg, 0.266 mmol) in THF (2 mL) and stirred for 6 h at rt. HCl (0.266 mL, 1 M) was added and the mixture was extracted with EtOAc. The combined organics were washed with brine, dried over Na2SO4 and concentrated in vacuo. The product 2E was used without further purification. MS (ESI) m/z: 832.7 (M+H)+.

1. extractionthe mixture was extracted with EtOAc
2. washThe combined organics were washed with brine
3. dry with materialdried over Na2SO4
4. concentrationconcentrated in vacuo
5. customThe product 2E was used without further purification