反应详情

To an AcOEt (50 ml) solution of Compound 40 (2.24 g) obtained in Example 2, HCl (50 ml, 4.0 N in AcOEt) was added and the mixture was stirred at room temperature for 15 hours, and after adding pentane (140 ml), the mixture was stirred for 8 days. The residue obtained by concentrating the reaction mixture was recrystallized (MeOH/Et2O) to give the titled compound (2.23 g, colorless powder.)

1. stirringthe mixture was stirred for 8 days
2. customThe residue obtained
3. concentrationby concentrating the reaction mixture
4. customwas recrystallized (MeOH/Et2O)