反应详情

温度

85 °C

8 g Potassium carbonate and 2.7 g 3-hydroxy-4-methoxybenzonitrile (for synthesis see Example 47) was dissolved in 25 mL dimethylformamide. 2.15 mL 2-Bromopropane was added and the mixture stirred at 85° C. for 3 h. The mixture was concentrated, diluted in ethyl acetate and washed with water (×2) and saturated sodium chloride solution, dried over magnesium sulfate and concentrated.

1. concentrationThe mixture was concentrated
2. additiondiluted in ethyl acetate
3. washwashed with water (×2) and saturated sodium chloride solution
4. dry with materialdried over magnesium sulfate
5. concentrationconcentrated