Tin tetrachloride → HCID 178433948, compound

HRID 722209Notes

Reaction equation

HRID 722209 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:12][C:11]([CH3:13])=[N:10][N:9]=2)=[CH:4][C:3]=1[N+:14]([O-])=O.[Sn](Cl)(Cl)(Cl)Cl>C(OCC)(=O)C>[NH2:14][C:3]1[CH:4]=[C:5]([C:8]2[NH:12][C:11]([CH3:13])=[N:10][N:9]=2)[CH:6]=[CH:7][C:2]=1[Cl:1]

Participants

4

Reactant 2

HCID 24287Tin tetrachlorideHCID 178433950HCID 178433950, compound

Product 1

HCID 178433948HCID 178433948, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The mixture consisting of 120 mg of 3-(4-chloro-3-nitrophenyl)-5-methyl-4H-[1,2,4]triazole, 30 ml of ethyl acetate and 644 mg of tin chloride was heated to reflux for 6 hours. After cooling, the mixture was washed with water, and the organic phase was dried over sodium sulfate and concentrated at 40° C. under reduced pressure.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 6 hours
  3. temperatureAfter cooling
  4. washthe mixture was washed with water
  5. dry with materialthe organic phase was dried over sodium sulfate
  6. concentrationconcentrated at 40° C. under reduced pressure

Sources & evidence

ORD record
ord-d30d8f3289674bd2b396e4e962eb9075
Source dataset
uspto-grants-2006_11
Patent number
US07138414B2

Reaction notes

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