反应详情

4-Acetaminoaniline was reacted with carbonyidiimidazole and (2,2-dimethoxyethyl)-(4-phenoxyphenyl)amine as described in example 92, followed by treatment of the crude product with trifluoroacetic acid at 80° C. The product is precipitated on addition of ethyl acetate/heptane 1:1. The precipitated solid was filtered off and dried in a vacuum oven at 40° C. The product with the molecular weight of 385.43 (C23H17N3O2); MS (ESI): 386 ([M+H]+) was obtained in this way.

1. customThe product is precipitated on addition of ethyl acetate/heptane 1:1
2. filtrationThe precipitated solid was filtered off
3. customdried in a vacuum oven at 40° C
4. customMS (ESI): 386 ([M+H]+) was obtained in this way