Bromobenzene → Biphenyl

HRID 724461Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8]1(B(O)O)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:2]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 7961Bromobenzene

HCID 66827Phenylboronic Acid

Product 1

HCID 7095Biphenyl

Procedure

Table 2 summarizes the coupling experiments of bromobenzene and benzeneboronic acid to give biphenyl under bis(N-pivaloyl-N′-butylbenzamidine)palladium(II) chloride catalysis.

Sources & evidence

ORD record: ord-180c7aa5a0bf4613ab7df0e1ae9450a3
Source dataset: uspto-grants-2006_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07141687B2

Reaction notes

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