反应详情

3.0 g of 2,6-dibromo-4-nitro-aniline are dissolved in 150 ml of ethanol, 150 ml of ethyl acetate and 30 ml of dimethylformamide and, after addition of 0.5 g of platinum-on-charcoal (5%), are hydrogenated in a Parr apparatus at room temperature under a hydrogen pressure of 1.5 bar for 1 hour. After cooling, the mixture is filtered, the solvent is distilled off in a rotary evaporator and the residue is purified by column chromatography.

1. customare hydrogenated in a Parr apparatus at room temperature under a hydrogen
2. customfor 1 hour
3. temperatureAfter cooling
4. filtrationthe mixture is filtered
5. distillationthe solvent is distilled off in a rotary evaporator
6. customthe residue is purified by column chromatography