Benzene → [1,1'-Biphenyl]-2-carbonyl chloride

HRID 726702Notes

Reaction equation

HRID 726702 reaction equation
[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[C:9](O)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CN(C)C=O.C(Cl)(=O)C([Cl:24])=O.C1C=CC=CC=1>C(Cl)Cl>[C:1]1([C:7]2[CH:15]=[CH:14][CH:13]=[CH:12][C:8]=2[C:9]([Cl:24])=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

6

Reactant 4

HCID 241BenzeneHCID 6228DimethylformamideHCID 65578Oxalyl chlorideHCID 70357o-Phenylbenzoic acid

Product 1

HCID 12563768[1,1'-Biphenyl]-2-carbonyl chloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

o-Phenylbenzoic acid (163 mg) was dissolved in 5 ml of methylene chloride, a catalytically effective amount of N,N-dimethylformamide was added dropwise, and 0.165 ml of oxalyl chloride was added dropwise. After 3 hours of stirring at room temperature, benzene was added and the solvent was evaporated to obtain o-phenylbenzoic acid chloride.

Workup

  1. customthe solvent was evaporated

Sources & evidence

ORD record
ord-797bf1e57b8046ebb97ba8ccb29a2e67
Source dataset
uspto-grants-1998_01
Patent number
US05710150

Reaction notes

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