反应详情

温度

70 °C

To a solution of 4-fluoronitrobenzene (0.50 mL) and phenol (443 mg) in 5.0 mL of dimethylformamide was added K2CO3 (1.27 g). The reaction was warmed to 70° C. for 20 h, then cooled to room temperature and poured into ethyl acetate and water. The organic layer was washed with water, sat. aq. NaHCO3 solution, and brine. The solution was dried (Na2SO4), filtered, and concentrated in vacuo to provide the crude product as a yellow solid.

1. temperaturecooled to room temperature
2. washThe organic layer was washed with water, sat. aq. NaHCO3 solution, and brine
3. dry with materialThe solution was dried (Na2SO4)
4. filtrationfiltered
5. concentrationconcentrated in vacuo