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HRID727762

反应详情

EQUATION

反应方程式

HRID 727762 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：O=C(c1ccccc1O)C(F)(F)F
HCID2761164

2-Trifluoroacetylphenol

C8H5F3O2

结构：CCCCC[C@H]1CC[C@H](CBr)CC1
HCID178444389

未命名化合物

PRODUCTS

生成物

1
结构：CCCCC[C@H]1CC[C@H](COc2ccc(C(=O)C(F)(F)F)cc2)CC1
HCID178444531

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

CONDITIONS

反应条件

温度
140 °C

PROCEDURE

实验过程

A mixture of 0.1 mol of trifluoroacetylphenol, 0.11 mol of trans-4-pentylcyclohexylmethyl bromide, 0.3 mol of K2CO3 and 250 ml DMF is heated at 140° C. for 10 hours. Customary work-up and crystallization give 4-(trans-4-pentylcyclohexylmethoxy)-1-trifluoroacetylbenzene, mp. 60° C., Δε=13.7.

WORKUP

后处理

  1. customCustomary work-up and crystallization