HRID728967

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID177

Acetaldehyde

C2H4O

HCID751

(+/-)-Glyceraldehyde

C3H6O3

HCID14923

Ammonium hydroxide

H5NO

结构：CCOc1ccc(N2CCN(Cc3ccccc3)C(C(=O)N(CCOC)c3ccc(N)cc3)C2)cc1

HCID14998839

未命名化合物

PRODUCTS

生成物

结构：CCOc1ccc(N2CCN(Cc3ccccc3)C(C(=O)N(CCOC)c3ccc(-n4ccnc4C)cc3)C2)cc1

HCID14998778

未命名化合物

PROCEDURE

实验过程

In a manner similar to Preparation 34, react N-(4-aminophenyl)-4-(4-ethoxyphenyl)-N-(2-methoxyethyl)-1-(phenylmethyl)-2-piperazinecarboxamide with glyceraldehyde, acetaldehyde and ammonium hydroxide to obtain the title compound.

WORKUP

后处理

customIn a manner similar to Preparation 34

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8745d5e2b1044781a1e3a4275bdc9ebf
来源数据集: uspto-grants-1991_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05051422
来源说明: uspto-grants-1991_09

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]([CH2:33][CH2:34][O:35][CH3:36])[C:9]([CH:11]2[CH2:16][N:15]([C:17]3[CH:22]=[CH:21][C:20]([O:23][CH2:24][CH3:25])=[CH:19][CH:18]=3)[CH2:14][CH2:13][N:12]2[CH2:26][C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)=[O:10])=[CH:4][CH:3]=1.O=C[CH:39]([CH2:41]O)O.[CH:43](=O)[CH3:44].[OH-].[NH4+:47]>>[CH2:24]([O:23][C:20]1[CH:21]=[CH:22][C:17]([N:15]2[CH2:14][CH2:13][N:12]([CH2:26][C:27]3[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=3)[CH:11]([C:9]([N:8]([CH2:33][CH2:34][O:35][CH3:36])[C:5]3[CH:4]=[CH:3][C:2]([N:1]4[CH:44]=[CH:43][N:47]=[C:41]4[CH3:39])=[CH:7][CH:6]=3)=[O:10])[CH2:16]2)=[CH:18][CH:19]=1)[CH3:25]