Methylamine → HCID 12591561, compound

HRID 745459Notes

Reaction equation

HRID 745459 reaction equation
[CH3:1][NH2:2].[CH2:3]([CH:19]1O[CH:20]1[CH2:21][O:22][CH2:23][CH:24]1[O:42][CH:25]1CCCCCCCCCCCCCCCC)[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]CCC>O1CCCC1>[CH2:21]([O:22][CH2:23][CH:24]([OH:42])[CH2:25][NH:2][CH3:1])[CH2:20][CH2:19][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 86740887Hexadecyl-2.3-epoxypropylether

Product 1

HCID 12591561HCID 12591561, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A cooled mixture of 15.5 g of methylamine, 50 cc. of tetrahydrofurane and 15 g of hexadecyl-2.3-epoxypropylether is heated to 60° C. for 2 hours in an autoclave, cooled and evaporated in a vacuo. The residue is purified by column chromatography (silicic acid gel//chloroform/methanol).

Workup

  1. temperaturecooled
  2. customevaporated in a vacuo
  3. customThe residue is purified by column chromatography (silicic acid gel//chloroform/methanol)

Sources & evidence

ORD record
ord-b251f801dfc540c08ed8025e6bdc4c92
Source dataset
uspto-grants-1986_07
Patent number
US04599205

Reaction notes

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