反应详情

109 mg (0.55 mmol) of 3-(2-aminoethoxy)benzonitrile hydrochloride, 85 mg (0.55 mmol) of 1-hydroxybenzotriazole (hydrate), 105 mg (0.55 mmol) of 1-(3-dimethylaminopropyl)-3-ethyl carbodiimide hydrochloride, 61 mg (0.6 mmol) of triethylamine, and 100 mg (0.55 mmol) of p-chloro-cinnamic acid were used, and the title compound was obtained in the same manner as in step 1 in Example 211.