HRID74963

反应详情

EQUATION

反应方程式

HRID 74963 的结构方程式

REACTANTS

反应物

4

结构：[Li+].[OH-]

Lithium hydroxide anhydrous

HLiO

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

2 次

结构：Cc1ccc(S(=O)(=O)n2cc(B3OC(C)(C)C(C)(C)O3)c3cc(Cl)cnc32)cc1

5-Chloro-1-(4-methylbenzene-1-sulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine

C20H22BClN2O4S

结构：Cc1ccc(S(=O)(=O)n2cc(-c3ncc(F)c(S(C)=O)n3)c3cc(Cl)cnc32)cc1

未命名化合物

PRODUCTS

生成物

1

结构：O=C1NCCOCC1Nc1nc(-c2c[nH]c3ncc(Cl)cc23)ncc1F

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

3

结构：c1ccncc1

Pyridine

C5H5N

结构：CN(C)C=O

N,N-Dimethylformamide

C3H7NO

3 次

结构：ClCCl

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Amine, HATU, DMF; (b) BOC2O, NH4CO3H, pyridine, DMF; (c) i: Amine, HATU, DMF; then ii: 1N LiOH.