反应详情

To 4-Hydroxy benzaldehyde (10 g) in acetone (200 ml), potassium carbonate (16.96 g) was added and stirred. To this, benzyl bromide (12.67 ml) was added and the reaction mixture was refluxed for 3 hours and then cooled. The reaction mixture was filtered and the filtrate was concentrated to obtain pale brown colored oil which got solidified at room temperature. Solid was crystallized from DCM-Petroleum ether to obtain the title compound as pale yellow solid. Yield: 13 g (74%); 1HNMR (CDCl3; 300 MHz): δ 9.91 (s, 1H), 7.87 (d, 2H), 7.33-7.43 (m, 5H), 7.12 (d, 21-1) 5.17 (s, 2H).

1. temperaturethe reaction mixture was refluxed for 3 hours
2. temperaturecooled
3. filtrationThe reaction mixture was filtered
4. concentrationthe filtrate was concentrated
5. customto obtain pale brown colored oil which
6. customgot solidified at room temperature
7. customSolid was crystallized from DCM-Petroleum ether