HRID798935

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID313

Hydrochloric Acid

ClH

HCID6228

N,N-Dimethylformamide

C3H7NO

HCID81531

Diisopropylethylamine

C8H19N

HCID583453

1-Cyclohexyl-1,2,3,4-tetrahydro-isoquinoline

C15H21N

HCID20394181

1-Benzyl-4-hydroxypiperidine-4-carboxylic acid

C13H17NO3

PRODUCTS

生成物

结构：O=C(N1CCc2ccccc2C1C1CCCCC1)C1(O)CCN(Cc2ccccc2)CC1

HCID59396561

1-benzyl-4-[(1-cyclohexyl-3,4-dihydroisoquinolin-2(1H)-yl)carbonyl]piperidin-4-ol

C28H36N2O2

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-50be0d49578247c48f9b8078d258911c
来源数据集: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Test data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:15])[OH:16])([OH:17])[CH2:12][CH2:13]1.[CH:18]([N:19]([CH2:20][CH3:21])[CH:22]([CH3:23])[CH3:24])([CH3:25])[CH3:26].[CH:28]1([CH:34]2[NH:35][CH2:36][CH2:37][c:38]3[cH:39][cH:40][cH:41][cH:42][c:43]32)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]1.[ClH:27].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([C:14](=[O:16])[N:35]2[CH:34]([CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]3)[c:43]3[c:38]([cH:39][cH:40][cH:41][cH:42]3)[CH2:37][CH2:36]2)([OH:17])[CH2:12][CH2:13]1