Hydrochloric Acid → methyl 15-cyclohexyl-6-[2-(dimethylamino)ethyl]-7-oxo-6,7,8,9-tetrahydro-5H-indolo[2,1-a][2,6]benzodiazonine-12-carboxylate
Reaction equation
[CH3:74][CH2:75][O:76][C:77]([CH3:78])=[O:79].[CH:1]1([c:7]2[c:8](-[c:25]3[c:26]([CH2:31][NH:32][CH2:33][CH2:34][N:35]([CH3:36])[CH3:37])[cH:27][cH:28][cH:29][cH:30]3)[n:9]([CH2:20][CH2:21][C:22](=[O:23])[OH:24])[c:10]3[cH:11][c:12]([C:16](=[O:17])[O:18][CH3:19])[cH:13][cH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:38]([N:39]([CH2:40][CH3:41])[CH:42]([CH3:43])[CH3:44])([CH3:45])[CH3:46].[Cl:71][CH2:72][Cl:73].[ClH:80].[P-:47]([F:48])([F:49])([F:50])([F:51])([F:52])[F:53].[n:54]1([O:55][C:56]([N:57]([CH3:58])[CH3:59])=[N+:60]([CH3:61])[CH3:62])[c:63]2[n:64][cH:65][cH:66][cH:67][c:68]2[n:69][n:70]1>>[CH:1]1([c:7]2[c:8]3[n:9]([c:10]4[cH:11][c:12]([C:16](=[O:17])[O:18][CH3:19])[cH:13][cH:14][c:15]24)[CH2:20][CH2:21][C:22](=[O:24])[N:32]([CH2:33][CH2:34][N:35]([CH3:36])[CH3:37])[CH2:31][c:26]2[c:25]-3[cH:30][cH:29][cH:28][cH:27]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
8
Reactant 7
HCID 313Hydrochloric Acid
HCID 6344Dichloromethane
HCID 8857Ethyl Acetate
HCID 9886Hexafluorophosphate
HCID 81531Diisopropylethylamine
HCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminium
HCID 685099363-[3-cyclohexyl-2-[2-({[2-(dimethylamino)ethyl]amino}methyl)phenyl]-6-(methoxycarbonyl)-1H-indol-1-yl]propanoic acidProduct 1
Sources & evidence
- ORD record
- ord-eccab57623da44fa9df361258084a4b8
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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