Methanol → Hexahydrofuro(2,3-b)furan-3-ol

HRID 800760Notes

Reaction equation

HRID 800760 reaction equation
[Al+3:22].[C:1]([CH:2]([O:3][SiH:4]([CH3:5])[CH3:6])[CH:7]1[O:8][C:9](=[O:10])[CH2:11][CH:12]1[CH:13]1[O:14][CH2:15][CH2:16][O:17]1)([CH3:18])([CH3:19])[CH3:20].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH2:56]([CH2:57][OH:58])[CH3:59].[CH3:54][OH:55].[Cl:51][CH2:52][Cl:53].[H-:21].[H-:24].[H-:25].[H-:26].[Li+:23].[O:27]1[CH:28]([CH:32]([CH:33]([CH2:34][OH:35])[OH:36])[CH2:37][CH2:38][OH:39])[O:31][CH2:30][CH2:29]1.[OH2:45]>>[CH:28]12[CH:32]([CH:33]([OH:36])[CH2:34][O:35]1)[CH2:37][CH2:38][O:39]2

Participants

11

Reactant 10

HCID 887MethanolHCID 962WaterHCID 10311-PropanolHCID 6344DichloromethaneHCID 8028Tetrahydrofuran2×HCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 1732105485-(1-Dimethylsilyloxy-2,2-dimethylpropyl)-4-(1,3-dioxolan-2-yl)oxolan-2-oneHCID 178520685HCID 178520685, compound

Product 1

HCID 9898832Hexahydrofuro(2,3-b)furan-3-ol

Sources & evidence

ORD record
ord-e91ae6d1ade3416b997601b303a2916c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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