Water → 1-{4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-naphthalen-1-yl}-1H-[1,2,4]triazole

HRID 800905Notes

Reaction equation

HRID 800905 reaction equation
[CH3:41][CH2:42][N:43]([CH2:44][CH3:45])[CH2:46][CH3:47].[Cl:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8].[Cl:27][c:28]1[cH:29][c:30]([Cl:40])[cH:31][c:32]([C:34](=[CH2:35])[C:36]([F:37])([F:38])[F:39])[cH:33]1.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[OH2:53].[n:9]1(-[c:14]2[cH:15][cH:16][c:17]([CH:24]=[N:25][OH:26])[c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]23)[n:10][cH:11][n:12][cH:13]1>>[n:9]1(-[c:14]2[cH:15][cH:16][c:17]([C:24]3=[N:25][O:26][C:34]([c:32]4[cH:31][c:30]([Cl:40])[cH:29][c:28]([Cl:27])[cH:33]4)([C:36]([F:37])([F:38])[F:39])[CH2:35]3)[c:18]3[cH:19][cH:20][cH:21][cH:22][c:23]23)[n:10][cH:11][n:12][cH:13]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 8471TriethylamineHCID 31398ChlorosuccinimideHCID 231598231,3-Dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzeneHCID 866581564-[1,2,4]Triazol-1-yl-naphthalene-1-carbaldehyde oxime

Product 1

HCID 468423961-{4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-naphthalen-1-yl}-1H-[1,2,4]triazole

Sources & evidence

ORD record
ord-adc1005bf1b849c492d24cebcbd7389d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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