Dimethylformamide → Methyl 1-benzyl-5-(nitromethylene)-2-pyrrolidinecarboxylate

HRID 802223Notes

Reaction equation

HRID 802223 reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N+:9]1=[C:13]([S:14][CH3:15])[CH2:12][CH2:11][CH:10]1[C:16](=[O:17])[O:18][CH3:19].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32].[I-:1].[N+:20](=[O:21])([O-:22])[CH3:23]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[N:9]1[CH:10]([C:16](=[O:17])[O:18][CH3:19])[CH2:11][CH2:12][C:13]1=[CH:23][N+:20](=[O:21])[O-:22]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6375NitromethaneHCID 30165Iodide IonHCID 81531DiisopropylethylamineHCID 23525580methyl 1-benzyl-5-methylsulfanyl-3,4-dihydro-2H-pyrrol-1-ium-2-carboxylate

Product 1

HCID 66846370Methyl 1-benzyl-5-(nitromethylene)-2-pyrrolidinecarboxylate

Sources & evidence

ORD record
ord-51b0302435e24579b0e03fd3312e63ce
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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