Dimethylformamide → 4-(methyl(pyridin-3-yl)amino)-N-(4-methylthiazol-2-yl)picolinamide

HRID 802590Notes

Reaction equation

HRID 802590 reaction equation
[CH3:18][c:19]1[n:20][c:21]([NH2:24])[s:22][cH:23]1.[CH3:1][N:2]([c:3]1[cH:4][c:5]([C:9](=[O:10])[OH:11])[n:6][cH:7][cH:8]1)[c:12]1[cH:13][n:14][cH:15][cH:16][cH:17]1.[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[Cl:58][CH2:59][Cl:60].[F:25][P-:26]([F:27])([F:28])([F:29])([F:30])[F:31].[O:61]=[CH:62][N:63]([CH3:64])[CH3:65].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[n:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[CH3:1][N:2]([c:3]1[cH:4][c:5]([C:9](=[O:11])[NH:24][c:21]2[n:20][c:19]([CH3:18])[cH:23][s:22]2)[n:6][cH:7][cH:8]1)[c:12]1[cH:13][n:14][cH:15][cH:16][cH:17]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 741432-Amino-4-methylthiazoleHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 58349312HCID 58349312, compound

Product 1

HCID 867621734-(methyl(pyridin-3-yl)amino)-N-(4-methylthiazol-2-yl)picolinamide

Sources & evidence

ORD record
ord-b96fc2b392494b6d971e83f4fb5e9427
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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