Ammonium → Tert-butyl 4-[4-[4-(benzoyloxymethyl)-2-oxo-1,3-oxazolidin-3-yl]-3-fluorobenzoyl]piperazine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([C:14]([c:15]2[cH:16][c:17]([F:22])[c:18]([Br:21])[cH:19][cH:20]2)=[O:23])[CH2:12][CH2:13]1.[C:40](=[O:41])([O-:42])[O-:43].[CH3:46][NH:47][CH2:48][CH2:49][NH:50][CH3:51].[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[CH3:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1.[Cl-:52].[Cu:54][I:55].[K+:44].[K+:45].[NH4+:53].[O:24]=[C:25]1[O:26][CH2:27][CH:28]([CH2:30][O:31][C:32]([c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)=[O:39])[NH:29]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([C:14]([c:15]2[cH:16][c:17]([F:22])[c:18]([N:29]3[C:25](=[O:24])[O:26][CH2:27][CH:28]3[CH2:30][O:31][C:32]([c:33]3[cH:34][cH:35][cH:36][cH:37][cH:38]3)=[O:39])[cH:19][cH:20]2)=[O:23])[CH2:12][CH2:13]1Participants
11
Reactant 10
HCID 223Ammonium
HCID 312Chloride
HCID 813Potassium Cation2×
HCID 1140Toluene
HCID 8070N,N'-Dimethylethylenediamine
HCID 8857Ethyl Acetate
HCID 19660Carbonate Ion
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 5068017(2-Oxo-1,3-oxazolidin-4-yl)methyl benzoate
HCID 58484677tert-Butyl 4-[(4-bromo-3-fluorophenyl)carbonyl]piperazine-1-carboxylateProduct 1
Sources & evidence
- ORD record
- ord-9666c9844a76469b912128198bbc69c7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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