Dichloromethane → 3-[(p-chlorophenyl)ethynyl]-8-fluoro-4,5-dihydro-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one

HRID 805638Notes

Reaction equation

[CH2:28]([NH:29][CH2:30][CH3:31])[CH3:32].[CH2:33]([Cl:34])[Cl:35].[Cl:19][c:20]1[cH:21][cH:22][c:23]([C:26]#[CH:27])[cH:24][cH:25]1.[Cu:77][I:78].[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[C:7](=[O:17])[N:8]([CH3:16])[CH2:9][c:10]1[n:11]-2[cH:12][n:13][c:14]1[I:15].[Pd:36]([Cl:37])[Cl:38].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[c:58]1([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[cH:72][cH:73][cH:74][cH:75][cH:76]1>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[C:7](=[O:17])[N:8]([CH3:16])[CH2:9][c:10]1[n:11]-2[cH:12][n:13][c:14]1[C:27]#[C:26][c:23]1[cH:22][cH:21][c:20]([Cl:19])[cH:25][cH:24]1