Water → 2-Amino-N-(4-chloro-5-phenoxy-thiophen-2-ylmethyl)-nicotinamide
Reaction equation
[C:38](#[N:39])[CH3:40].[CH3:24][N:25]([CH3:26])[CH:27]=[O:28].[Cl:29][N:30]1[C:31](=[O:32])[CH2:33][CH2:34][C:35]1=[O:36].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH2:7][c:8]2[s:9][c:10]([O:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[cH:11][cH:12]2)[cH:20][cH:21][cH:22][n:23]1.[OH2:37].[OH:41][C:42]([C:43]([F:44])([F:45])[F:46])=[O:47]>>[NH2:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][CH2:7][c:8]2[s:9][c:10]([O:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)[c:11]([Cl:29])[cH:12]2)[cH:20][cH:21][cH:22][n:23]1Participants
7
Sources & evidence
- ORD record
- ord-299edb6d918c4a18a814e5cd826801a7
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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