Triethylamine → 2-[(Phenyl)ethynyl]phenyl-2-propanone

HRID 805982Notes

Reaction equation

HRID 805982 reaction equation
[Br:1][c:2]1[c:3]([CH2:8][C:9]([CH3:10])=[O:11])[cH:4][cH:5][cH:6][cH:7]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[Cu:68][I:69].[Pd:27]([Cl:28])[Cl:29].[Pd:70].[c:12]1([C:18]#[CH:19])[cH:13][cH:14][cH:15][cH:16][cH:17]1.[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1.[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1>>[c:2]1([C:19]#[C:18][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[c:3]([CH2:8][C:9]([CH3:10])=[O:11])[cH:4][cH:5][cH:6][cH:7]1

Participants

8

Reactant 7

HCID 8471TriethylamineHCID 10821PhenylacetyleneHCID 11776Triphenylphosphine2×HCID 23938PalladiumHCID 24290Palladium ChlorideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 27340921-(2-Bromophenyl)propan-2-one

Product 1

HCID 139106162-[(Phenyl)ethynyl]phenyl-2-propanone

Sources & evidence

ORD record
ord-788fa7b96d0448c08a47a024e5de2564
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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