Triethylamine → Benzyl-[-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-methylamine

HRID 806367Notes

Reaction equation

HRID 806367 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH3:9])[C:10]1([c:13]2[cH:14][cH:15][c:16]([Br:19])[cH:17][cH:18]2)[CH2:11][CH2:12]1.[CH3:20][Si:21]([CH3:22])([CH3:23])[C:24]#[CH:25].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[Cu:33][I:34]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH3:9])[C:10]1([c:13]2[cH:14][cH:15][c:16]([C:25]#[C:24][Si:21]([CH3:20])([CH3:22])[CH3:23])[cH:17][cH:18]2)[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 22568936Benzyl-[1-(4-bromophenyl)-cyclopropyl]-methylamine

Product 1

HCID 69548036Benzyl-[-(4-trimethylsilanylethynyl-phenyl)-cyclopropyl]-methylamine

Sources & evidence

ORD record
ord-f12f7089f3244cc1a368a09a3ff3bb13
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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