3-Hydroxybenzyl alcohol → Benzenemethanol, 3-(2-quinolinylmethoxy)-

HRID 806463Notes

Reaction equation

HRID 806463 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:2][CH2:3][c:4]1[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]2[cH:12][cH:13]1.[ClH:1].[K+:27].[K+:28].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[OH2:29].[OH:14][CH2:15][c:16]1[cH:17][cH:18][cH:19][c:20]([OH:21])[cH:22]1>>[CH2:3]([c:4]1[n:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]2[cH:12][cH:13]1)[O:21][c:20]1[cH:19][cH:18][cH:17][c:16]([CH2:15][OH:14])[cH:22]1

Participants

9

Reactant 8

HCID 1023-Hydroxybenzyl alcoholHCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 203942-(Chloromethyl)quinoline

Product 1

HCID 14650410Benzenemethanol, 3-(2-quinolinylmethoxy)-

Sources & evidence

ORD record
ord-eda62c5b319a4a82a4908e96029d3fc9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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