Potassium Cation → (2-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)methanol

HRID 807397Notes

Reaction equation

HRID 807397 reaction equation
[Al+3:19].[C:30]([CH:31]([CH:32]([C:33]([O-:34])=[O:35])[OH:36])[OH:37])([O-:38])=[O:39].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:24][CH2:25][O:26][C:27]([CH3:28])=[O:29].[CH:1]1([c:4]2[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[n:13]2)[CH2:2][CH2:3]1.[H-:18].[H-:21].[H-:22].[H-:23].[K+:41].[Li+:20].[Na+:40]>>[CH:1]1([c:4]2[c:5]([CH2:6][OH:7])[cH:10][cH:11][c:12]([C:14]([F:15])([F:16])[F:17])[n:13]2)[CH2:2][CH2:3]1

Participants

10

Reactant 9

HCID 813Potassium CationHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 38061142,3-DihydroxybutanedioateHCID 59834808Methyl 2-cyclopropyl-6-(trifluoromethyl)nicotinate

Product 1

HCID 59834793(2-Cyclopropyl-6-(trifluoromethyl)pyridin-3-yl)methanol

Sources & evidence

ORD record
ord-f39f95f9f53b4128a0bd676129e4f9c0
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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