Dimethylformamide → N-(1-Adamantylmethyl)-5-chloro-2-vinylisonicotinamide

HRID 807995Notes

Reaction equation

HRID 807995 reaction equation
[C:1]12([CH2:11][NH:12][C:13]([c:14]3[cH:15][c:16]([Cl:21])[n:17][cH:18][c:19]3[Cl:20])=[O:22])[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2.[C:38]([c:39]1[cH:40][c:41]([CH3:42])[cH:43][c:44]([C:45]([CH3:46])([CH3:47])[CH3:48])[c:49]1[OH:50])([CH3:51])([CH3:52])[CH3:53].[CH2:23]([CH2:24][CH2:36][CH3:37])[Sn:25]([CH2:26][CH2:27][CH2:28][CH3:29])([CH2:30][CH2:31][CH2:32][CH3:33])[CH:34]=[CH2:35].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[CH3:60][N:61]([CH3:62])[CH:63]=[O:64]>>[C:1]12([CH2:11][NH:12][C:13]([c:14]3[cH:15][c:16]([CH:23]=[CH2:24])[n:17][cH:18][c:19]3[Cl:20])=[O:22])[CH2:2][CH:3]3[CH2:4][CH:5]([CH2:6][CH:7]([CH2:8]1)[CH2:9]3)[CH2:10]2

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 314042,6-Di-tert-butyl-4-methylphenolHCID 81998TributylvinyltinHCID 11416492N-(1-adamantylmethyl)-2,5-dichloroisonicotinamide

Product 1

HCID 21906707N-(1-Adamantylmethyl)-5-chloro-2-vinylisonicotinamide

Sources & evidence

ORD record
ord-9d4726096bd14849a34243995d66e136
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…